已关闭
收藏Anti-M6A Monoclonal Antibody - 产品详情 (solarbio.com)
| 英文名称 | Anti-M6A Monoclonal Antibody |
| 宿主 | Mouse |
| 克隆类型 | Monoclonal antibody |
| 亚型 | IgG3 |
| 交叉反应 | M6A ; Mouse ; Rat ; Human |
| 应用 | ELISA ; RIP ; DB ; IHC |
| 稀释比例 | IHC 1:2000-8000. RIP 1:1000-4000. DB 1:1000-4000. ELISA 1:2000-20000. |
| 靶标 | M6A |
| 别名 | 6-N-Methyladenoside;m6A;N6-methyladenosine;M6A |
| 背景说明 | m6A (N6-methyladenosine) is the most abundant internal modification in mammalian mRNA. This modification is installed by the m6A methyltransferases or termed writerssuch as METTL3 and METTL14, and can be reversed by demethylases that serve as erasers such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by m6A reader protein YTHDFs, which recognizes m6A and reduces the stability of target transcripts. m6A modification and its regulatory proteins play critical roles in cancer pathogenesis and progression. m6A modification is also invovled in viruses life cycles, suggesting that drugs targets to m6A pathway could be used for antiviral thereapy. |
| 纯化方法 | Protein A purification |
| 储存液 | Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
| 规格 | 50ul ; 100ul |
| 单位 | 支 |
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.

Immunohistochemistry of paraffin-embedded mouse testis using m6A antibody diluted at 1:4000.
BiotinCy3Cy3.5Cy5Cy5.5Cy7FITCHRPRBITCSAlexa Fluor 350SAlexa Fluor 405SAlexa Fluor 488SAlexa Fluor 532SAlexa Fluor 555SAlexa Fluor 568SAlexa Fluor 594SAlexa Fluor 633SAlexa Fluor 640SAlexa Fluor 647SAlexa Fluor 660SAlexa Fluor 680SAlexa Fluor 750