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收藏Anti-DUSP8 Polyclonal antibody - 产品详情 (solarbio.com)
| 英文名称 | Anti-DUSP8 Polyclonal Antibody |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human ; Rat ; Mouse |
| 应用 | IF ; WB |
| 稀释比例 | WB 1:1000-5000. IF 1:500-1000. |
| 靶标 | DUSP8 |
| 别名 | DUSP8;C11orf81;HB5;HVH-5;HVH8 |
| 背景说明 | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. |
| Swiss Prot | Q13202 |
| Gene ID | 1850 |
| 亚细胞定位 | Cytoplasm,Nucleus |
| 免疫原 | A synthetic peptide of human DUSP8 |
| Public Immunogen Range | 1-100aa |
| 理论分子量 | 65kDa |
| 实际分子量 | 66kDa |
| 纯化方法 | Affinity purification |
| 储存液 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
| 规格 | 50ul ; 100ul |
| 单位 | 支 |
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.

Western blot analysis with DUSP8 antibody diluted at 1:500;Lane: U-87MG Raji A431.

Immunofluorescence analysis of L929 cells using DUSP8 antibody diluted at 1:100.
BiotinCy3Cy3.5Cy5Cy5.5Cy7FITCHRPRBITCSAlexa Fluor 350SAlexa Fluor 405SAlexa Fluor 488SAlexa Fluor 532SAlexa Fluor 555SAlexa Fluor 568SAlexa Fluor 594SAlexa Fluor 633SAlexa Fluor 640SAlexa Fluor 647SAlexa Fluor 660SAlexa Fluor 680SAlexa Fluor 750