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Anti-STAT3 Polyclonal Antibody - 产品详情 (solarbio.com)
| 英文名称 | Anti-STAT3 Polyclonal Antibody |
| 中文名称 | 信号转导和转录激活因子3 |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Human ; Mouse ; Rat |
| 预测交叉反应 | Cow;Pig;Chicken |
| 应用 | WB ; IHC |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| 靶标 | STAT3 |
| 别名 | 1110034C02Rik; Acute Phase Response Factor; Acute-phase response factor; ADMIO; APRF; AW109958; DNA binding protein APRF; FLJ20882; HIES; MGC16063; Signal transducer and activator of transcription 3 (acute phase response factor); Signal transducer and activator of transcription 3; STAT 3; Stat3; STAT3_HUMAN; |
| 背景资料 | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Swiss Prot | P40763 |
| Gene ID | 6774 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human STAT3 |
| Public Immunogen Range | 690-740/770aa |
| 理论分子量 | 83/88kDa |
| 实际分子量 | 88kDa |
| 纯化方法 | Affinity purification |
| 储存液 | Buffer: PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
| 性状 | 液体 |
| 规格 | 50ul ; 100ul |
| 单位 | 支 |
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Immunohistochemistry of paraffin-embedded human ovarian cancer with STAT3 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded human breast cancer with STAT3 antibody diluted at 1:100.
Western blot analysis with STAT3 antibody diluted at 1:2000;Lane: K-562,NIH3T3,Mouse lung.
相关标记
BiotinCy3Cy3.5Cy5Cy5.5Cy7FITCHRPRBITCSAlexa Fluor 350SAlexa Fluor 405SAlexa Fluor 488SAlexa Fluor 532SAlexa Fluor 555SAlexa Fluor 568SAlexa Fluor 594SAlexa Fluor 633SAlexa Fluor 640SAlexa Fluor 647SAlexa Fluor 660SAlexa Fluor 680SAlexa Fluor 750
