索莱宝SolarbioK114147P Anti-MAP3K8 Polyclonal AntibodyK114147Psolarbio,索莱宝-易享

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K114147P Anti-MAP3K8 Polyclonal Antibody

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This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases

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品牌索莱宝Solarbio

地区中国,北京,北京市

货号 K114147P

产地国产

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100ul

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北京索莱宝科技有限公司

北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层

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北京索莱宝科技有限公司（Beijing Solarbio Science & Technology Co.,Ltd.）是一家从事生物学试剂及试剂盒的高科技生物企业。总部位于北京，并在全国设有经销或代理机构。产品因可靠而稳定的质量和完善的售后服务确立了“Solarbio”良好的品牌形象。公司秉承“以客户为中心、以产品为保障、以诚信为基础、以创新为宗旨”的发展理念，拥有专业的研发和质量检测团队以及先进的仓储和物流系统。“Solarbio”已经得到全国科研工作者的认可，成为广大经销商推崇的知名品牌。

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产品规格

品牌名称

索莱宝Solarbio

货号

K114147P

国产/进口

国产

规格

50ul,100ul

图文详情

Anti-MAP3K8 Polyclonal Antibody - 产品详情 (solarbio.com)

英文名称	Anti-MAP3K8 Polyclonal Antibody
中文名称	丝裂原活化蛋白激酶激酶8
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
交叉反应	Rat ; Human ; Mouse
应用	WB IHC
稀释比例	WB 1:2000-5000. IHC 1:25-100.
靶标	MAP3K8
别名	AURA2;c COT;Cancer Osaka thyroid oncogene;CCOT;COT;COT proto oncogene serine/threonine protein kinase;EST;ESTF;Ewing sarcoma transformant;FLJ10486;M3K8_HUMAN;MAP3K 8;MAP3K8;MEKK8;Mitogen activated protein kinase kinase kinase 8;Mitogen-activated protein kinase kinase kinase 8;Proto oncogene cCot;Proto-oncogene c-Cot;Serine/threonine protein kinase cot;Serine/threonine-protein kinase cot;TPL 2;TPL-2;TPL2;Tumor progression locus 2;
背景说明	This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.
Swiss Prot	P41279
Gene ID	1326
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide of human MAP3K8
Public Immunogen Range	295-345/467aa
理论分子量	50/53kDa
实际分子量	60kDa
纯化方法	Affinity purification
储存液	Buffer: PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3.
储存条件	Store at -20℃. Avoid freeze / thaw cycles.
规格	50ul ; 100ul
单位	支

以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。

These protocols are for reference only. Solarbio does not independently validate these methods.

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

实验图

Western blot analysis with MAP3K8 antibody diluted at 1:3000;Lane: 293T,HepG2,HMC1,HeLa,U937,A549,THP1,MCF7,K-562,HEL.

Immunohistochemistry of paraffin-embedded human thyroid cancer with MAP3K8 antibody diluted at 1:50.

实验图

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