索莱宝SolarbioK113647P Anti-IFITM1 Polyclonal AntibodyK113647Psolarbio,索莱宝-易享

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K113647P Anti-IFITM1 Polyclonal Antibody

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IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influen

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品牌索莱宝Solarbio

地区中国,北京,北京市

货号 K113647P

产地国产

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50ul

100ul

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北京索莱宝科技有限公司

北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层

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北京索莱宝科技有限公司（Beijing Solarbio Science & Technology Co.,Ltd.）是一家从事生物学试剂及试剂盒的高科技生物企业。总部位于北京，并在全国设有经销或代理机构。产品因可靠而稳定的质量和完善的售后服务确立了“Solarbio”良好的品牌形象。公司秉承“以客户为中心、以产品为保障、以诚信为基础、以创新为宗旨”的发展理念，拥有专业的研发和质量检测团队以及先进的仓储和物流系统。“Solarbio”已经得到全国科研工作者的认可，成为广大经销商推崇的知名品牌。

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产品规格图文详情技术文档

产品规格

品牌名称

索莱宝Solarbio

货号

K113647P

国产/进口

国产

规格

50ul,100ul

图文详情

Anti-IFITM1 Polyclonal Antibody - 产品详情 (solarbio.com)

中文名称	干扰素诱导跨膜蛋白1
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
交叉反应	Human
应用	IHC
稀释比例	IHC 1:50-200.
靶标	IFITM1
别名	1 8D; Dispanin subfamily A member 2c; DSPA2c; IFITM 2; Interferon induced transmembrane protein 2 (1 8D); Interferon induced transmembrane protein 2; Interferon inducible protein 1 8D; 9-27; CD 225; CD 225 antigen; CD225; CD225 antigen; Dispanin subfamily A member 2a; DSPA2a; IFI 17; IFI17; IFITM1; IFM1_HUMAN; Interferon induced protein 17; interferon induced transmembrane protein 1 (9-27); Interferon induced transmembrane protein 1; Interferon inducible protein 9-27; Interferon-induced protein 17; Interferon-induced transmembrane protein 1; Interferon-inducible protein 9-27; Leu 13; Leu 13 antigen; Leu-13 antigen; LEU13; 1 8U; Fragilis; IFITM3; IFM3_HUMAN; Interferon induced transmembrane protein 3 (1 8U); Interferon Induced Transmembrane Protein 3; Interferon inducible; Interferon inducible protein 1 8U; Interferon Inducible Protein 15; Interferon Inducible Protein Homolog; Interferon-induced transmembrane protein 3; Interferon-inducible protein 1-8U; IP15;
背景资料	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2, Marburg virus (MARV, Ebola virus (EBOV, Dengue virus (DNV, West Nile virus (WNV, human immunodeficiency virus type 1 (HIV-1 and hepatitis C virus (HCV. Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV and SARS-CoV-2 S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Inhibits SARS-CoV-2 S protein-mediated syncytia formation. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. In hepatocytes, IFITM proteins act in a coordinated manner to restrict HCV infection by targeting the endocytosed HCV virion for lysosomal degradation. IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a coordinated manner by trapping the virion in the endosomal pathway and targeting it for degradation at the lysosome.
Swiss Prot	P13164
Gene ID	8519
亚细胞定位	Cytoplasm Cell membrane
免疫原	A synthetic peptide of human IFITM1
Public Immunogen Range	75-125/125aa
理论分子量	14kDa
纯化方法	Affinity purification
储存液	Buffer: PBS with 50% Glycerol, 0.03% Proclin300, 0.5% BSA, pH 7.3.
储存条件	Store at -20℃. Avoid freeze / thaw cycles.
性状	液体
规格	50ul ; 100ul
单位	支

以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。

These protocols are for reference only. Solarbio does not independently validate these methods.

使用前请离心。如有问题请及时联系我们。

Quick spin before use. If you have any questions, please contact us.

实验图

Immunohistochemistry of paraffin-embedded human testis cancer with IFITM1 antibody diluted at 1:100.

Immunohistochemistry of paraffin-embedded human colorectal cancer with IFITM1 antibody diluted at 1:100.

实验图

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