Tetracycline hydrochloride是一种广谱抗生素。四环素通过阻止氨酰基-tRNA与细菌核糖体的结合来抑制细菌蛋白质合成。In VitroThe mycelia of strain S. rugosoannulata GL0170The initial concentrations of TET were 0, 10, 100, 250, and 500 μg/L, respectively.The growth status of the S. rugosoannulata was observed after cultivating;in the dark at 25 ?C for 8 days.Further measurements were conducted to assess the growth status of the mycelium ofS.;rugosoannulata;exposed to TET at concentrations of 0, 100, 250, 500,;1000 mg/L, respectively. The dry weight measurement method for;S. rugosoannulata mycelium was the same as described above.The effect of adding different concentrations of TET (0, 100, 250,;500, 1000, and 2000 mg/L),;100 mg/L OTC, and 100 mg/L DCL on the;growth of E. coli in S. rugosoannulata fermentation broth was verified.来源文献：Zhao S, Li X, Yao X, Wan W, Xu L, Guo L, Bai J, Hu C, Yu H. Transformation of antibiotics to non-toxic and non-bactericidal products by laccases ensure the safety of Stropharia rugosoannulata. J Hazard Mater. 2024 Sep 5;476:135099. doi: 10.1016/j.jhazmat.2024.135099. Epub 2024 Jul 3. PMID: 38981236.