图文详情
Influenza, commonly known as ‘the flu’, is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. Influenza viral nucleoprotein (NP) is highly conserved and is the most abundant non‑enzymatic viral protein, playing an essential role in encapsidating the viral RNA genome, regulating viral RNA transcription and replication, and mediating the assembly of ribonucleoprotein (RNP) complexes. Because of its high conservation and strong immunogenicity, NP is widely used as a diagnostic antigen and a target for antiviral research.