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Coagulation Factor IX is also known as F9, FIX, and P19. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa,and plays an important role in the intrinsic blood coagulation cascade. As a key component of the clotting cascade, Factor IX helps form stable blood clots and prevents excessive bleeding.