图文详情
MASP3 is a member of the MASP family. The MASP family proteins were first
discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated
serine proteases, but later, they were found to interact with ficolins, and later still, collectin-10
and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes
non-enzymatic factors (MAp19, MAp44). In this review, the association-specific factors of the lectin
pathway with haematologic malignancies and related infections are discussed.