Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant, HPLC-verified: Product Information
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Endotoxin<10 EU per mg protein
ActivityMeasured by its ability to inhibit proliferation of MPC-11 cells. The ED50 for this effect is 0.5-5ng/mL. The specific activity of recombinant human Activin A is >1000U/mg, which is calibrated against the human Activin A International Standard (NIBSC code: 91/626).
Protein ConstructionA DNA sequence encoding the Human / Mouse / Rat / Cynomolgus / Rhesus INHBA (NP_002183.1) (Gly311-Ser426) was expressed.
Expressed HostHEK293 Cells
SpeciesHuman, Mouse, Rat, Cynomolgus, Rhesus
Predicted N TerminalGly 311
Molecule MassThe recombinant human / mouse / rat / cynomolgus / rhesus INHBA consists of 116 amino acids and predicts a molecular mass of 13 kDa. It migrates as an approximately 16 kDa band in SDS-PAGE under reducing conditions and 25 KDa band in SDS-PAGE under non-reducing conditions.
FormulationSupplied as sterile 4mM HCl.
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
ShippingLiquid. It is shipped out with blue ice.
Stability & StorageSamples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
ReconstitutionA hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.






Activin A Background Information
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in many cell types and organs, such as gonads, pituitary gland, and placenta. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis. Also, Activin plays a role in wound repair and skin morphogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in the epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects.
Full Name
inhibin, beta A
Research Areas
Early Mesodermal Lineage Markers