规格/价格
20 µg:3870
100 µg:8940
Mesothelin Protein, Mouse, Recombinant (His & AVI Tag), HPLC-verified: 产品信息
- 纯度:≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
- 内毒素:< 1.0 EU per μg protein as determined by the LAL method.
- 生物素标记率:0.7-1 as determined by the HABA assay.
- 生物活性:Testing in progress
- 蛋白构建:A DNA sequence encoding the Mouse MSLN (Q61468-1) (Asp298-Ser600) was expressed with a C-terminal polyhistidine tag followed by an AVI tag. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
- 表达宿主:HEK293 Cells
- 种属:Mouse
- 预测 N 端:Asp 298
- 分子量:The recombinant Mouse MSLN consists of 329 amino acids and predicts a molecular mass of 37.41 kDa. It migrates as an approximately 47.83 kDa band in SDS-PAGE under reducing conditions.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- Please contact us for any concerns or special requirements.
- Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
- Please refer to the specific buffer information in the hard copy of CoA.
- In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
- Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
- Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
- Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- 复溶:A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Mesothelin Protein, Mouse, Recombinant (His & AVI Tag), HPLC-verified: 别称
MPF Protein, Mouse
Mesothelin 背景信息
The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.
全称
mesothelin