Description:NebuSelect™ Recombinant Human 2B4/CD244/SLAMF4, His-tag(Cat#NBL-243144) is expressed in HEK293 with His tag at the C-Terminus.It contains Cys22-Arg221.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 23.1 kDa. Due to glycosylation, the protein migrates to 45-70 kDa based on Bis-Tris PAGE result.

Target Name:2B4/CD244/SLAMF4Synonyms2B4; CD244 antigen; CD244; h2B4; NAIL; NKR2B4; Nmrk; SLAMF4

Target Information:2B4 (CD244) is expressed by memory-phenotype CD8 T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)