Description:NebuSelect™ Recombinant Cynomolgus AXL, His-tag(Cat#NBL-243085) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu33-Pro449.

Species:Cynomolgus

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 46.3 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Bis-Tris PAGE result.

Target Name:AXLSynonymsAxl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1

Target Information:Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)