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收藏Description:NebuSelect™ Recombinant Human B7-2/CD86, hFc-tag(Cat#NBL-243071) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Leu26-Pro247.
Species:Human
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 52 kDa. Due to glycosylation, the protein migrates to 75-90 kDa based on Bis-Tris PAGE result.
Target Name:B7-2/CD86SynonymsCD86 molecule; CD86; B70; B7-2 antigen; B72; B7-2; BU63; FUN-1; LAB72; MGC34413; CD28LG2
Target Information:B7-1 and B7-2 are homologous costimulatory ligands expressed on the surface of antigen presenting cells (APCs). Binding of these molecules to the T cell costimulatory receptors, CD28 and CTLA-4, is essential for the activation and regulation of T cell immunity. B7-1 and B7-2 do not form hetero-oligomers, underscoring the biological relevance of dimeric and monomeric state of B7-1 and B7-2, respectively.
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)