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收藏Description:NebuSelect™ Recombinant Human BST2, His-tag(Cat#NBL-243009) is expressed in HEK293 with His tag at the N-Terminus.It contains Asn49-Ser161.
Species:Human
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 14.5 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Bis-Tris PAGE result.
Target Name:BST2SynonymsBST-2; HM1.24 antigen; CD317; BST2; NPC-A-7; PDCA-1; TETHERIN
Target Information:Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)