Description:NebuSelect™ Recombinant Human CD300LF, hFc-tag(Cat#NBL-242920) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Thr20-Ser156.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 42.1 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:CD300LFSynonymsCLM-1; IREM-1; IgSF13; CD300F; IGSF13; NKIR; CD300f; CD300LF; CLIM1; DIgR2; LMIR3; NKIR; Pigr3

Target Information:Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. CD300lf as a proteinaceous receptor for MNoV. Interestingly, its paralogue CD300ld was also sufficient for MNoV infection in vitro. CD300lf is essential for both oral and parenteral MNoV infection and to elicit anti-MNoV humoral responses in vivo. human CD300lf (huCD300lf) is not essential for HNoV infection, nor does huCD300lf inhibit binding of HNoV virus-like particles to glycans.

Amino Acid Sequence: Thr20-Ser156

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)