Description:NebuSelect™ Recombinant FITC-Labeled Human Siglec-3/CD33, Avi-His-tag(Cat#NBL-242916) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp18-His259.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 29.6 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result.

Target Name:Siglec-3/CD33SynonymsCD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67

Target Information:Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.

Amino Acid Sequence: Asp18-His259

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)