Description:NebuSelect™ Recombinant Mouse CD8 alpha/CD8A, His-tag(Cat#NBL-242858) is expressed in HEK293 with His tag at the C-Terminus.It contains Lys28-Tyr196.

Species:Mouse

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 20 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Bis-Tris PAGE result.

Target Name:CD8 alpha/CD8ASynonymsCD8a; Lyt-2; CD8; Leu2; MAL; p32; CD8a molecule; OKT8 T-cell antigen

Target Information:CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.

Amino Acid Sequence: Lys28-Tyr196

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)