Description:NebuSelect™ Recombinant Mouse CD96/TACTILE, His-tag(Cat#NBL-242847) is expressed in HEK293 with His tag at the C-Terminus.It contains Val22-Met536.

Species:Mouse

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 57.9 kDa. Due to glycosylation, the protein migrates to 90-130 kDa based on Bis-Tris PAGE result.

Target Name:CD96/TACTILESynonymsCD96 molecule; CD96; DKFZp667E2122; TACTILE

Target Information:The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.

Amino Acid Sequence: Val22-Met536

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)