Description:NebuSelect™ Recombinant Human Complement Factor D/CFD, hFc-tag(Cat#NBL-242816) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Ile26-Ala253.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 51.2 kDa. Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result.

Target Name:Complement Factor D/CFDSynonymsAdipsin; C3 convertase activator; Complement factor D; CFD; PFD; DF; ADN; FACTOR D; AMBP-1; EC 3.4.21; EC 3.4.21.46

Target Information:Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)