Description:NebuSelect™ Recombinant Human CRTAM, His-tag(Cat#NBL-242770) is expressed in HEK293 with His tag at the C-Terminus.It contains Ser18-Gly287.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 31.1 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

Target Name:CRTAMSynonymsCD355 antigen; CD355; CRTAM

Target Information:Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)