Description:NebuSelect™ Recombinant Biotinylated Mouse GARP&Latent TGF beta 1 Complex, Avi-His-tag(Cat#NBL-242605) is expressed in HEK293 with His tag and Avi tag at the N-Terminus.It contains Ala18-Leu628(GARP)&Leu30-Ser390(Latent TGF beta 1).

Species:Mouse

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 66.6 kDa (GARP)&44.2 kDa (Latent TGF beta 1). Due to glycosylation, the protein migrates to 72-76 kDa (GARP)&13 kDa&45-47 kDa (Latent TGF beta 1) based on Bis-Tris PAGE result.

Target Name:GARP&Latent TGF beta 1 ComplexSynonymsLRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1

Target Information:GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)