Description:NebuSelect™ Recombinant Human GDF15, hFc-tag(Cat#NBL-242597) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Ala197-Ile308.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Target Name:GDF15SynonymsGDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta

Target Information:Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)