Description:NebuSelect™ Recombinant Human GFRA3, His-tag(Cat#NBL-242585) is expressed in HEK293 with His tag at the C-Terminus.It contains Asp32-Trp382.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 40.3 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Bis-Tris PAGE result.

Target Name:GFRA3SynonymsGDNFR-alpha-3; GFR-alpha-3; GFRA3; GFR alpha3; GPI-linked receptor

Target Information:GDNF (glial-cell-line derived neurotrophic factor) is a potent neurotrophic factor for dopaminergic neurons. Neuropsychiatric diseases and their treatments are associated with alterations in the levels of both GDNF and its receptor family (GDNF family receptor alpha or GFRA). GFRA1, GFRA2 and GFRA3 are located in chromosomal regions with suggestive linkage to schizophrenia.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)