Description:NebuSelect™ Recombinant Human GITR/TNFRSF18, His-tag(Cat#NBL-242556) is expressed in HEK293 with His tag at the C-Terminus.It contains Gln26-Glu161.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 15.4 kDa. Due to glycosylation, the protein migrates to 25-28 kDa based on Bis-Tris PAGE result.

Target Name:GITR/TNFRSF18SynonymsCD357; GITR; GITR-D; TNFRSF18; AITR

Target Information:GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)