Description:NebuSelect™ Recombinant Human HMGB1, His-tag(Cat#NBL-242545) is expressed in HEK293 with His tag at the C-Terminus.It contains Met1-Glu215.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 26 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.

Target Name:HMGB1SynonymsHMGB1; HMG1; HMG3; SBP-1; HMG-1

Target Information:High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number of experimental models of infectious and sterile inflammation.

Amino Acid Sequence: Met1-Glu215

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)