Description:NebuSelect™ Recombinant Human ICOS/CD278, His-tag(Cat#NBL-242537) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu21-Gln134.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 14.6 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Bis-Tris PAGE result.

Target Name:ICOS/CD278SynonymsAILIM; CD278; CRP-1; CVID1; ICOS; MGC39850

Target Information:Inducible co-stimulator (ICOS), also called AILIM (activiation-inducible lymphocyte immunomediatory molecule) and CRP-1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. Human ICOS is a homodimeric type I transmembrane protein consisting of 199 amino acids (aa) with a putative 20 aa signal sequence, a 121 aa extracellular domain, a 23 aa transmembrane region, and a 35 aa cytoplasmic domain.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)