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收藏Description:NebuSelect™ Recombinant Human IFN gamma R1/IFNGR1, hFc-tag(Cat#NBL-242530) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Glu18-Gly245.
Species:Human
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Target Name:IFN gamma R1/IFNGR1SynonymsIFN-gamma-R1; CDw119; CD119; IFNGR1; IFNGR; AVP; FLJ45734; IFN-gamma R1; IFN-gR1; type 2
Target Information:IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)