Description:NebuSelect™ Recombinant Mouse IFN alpha/beta R1, Avi-His-tag(Cat#NBL-242527) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu27-Thr429.

Species:Mouse

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 46.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Target Name:IFN alpha/beta R1SynonymsAVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC

Target Information:IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)