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收藏Description:NebuSelect™ Recombinant Mouse IgE, Avi-His-tag(Cat#NBL-242524) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp198-Ser421.
Species:Mouse
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Target Name:IgESynonymsIg epsilon chain C region;IgE
Target Information:Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.
Amino Acid Sequence: Asp198-Ser421
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)