Description:NebuSelect™ Recombinant Human IgG1 Fc(Cat#NBL-242517) is expressed in HEK293 without tag.It contains Asp104-Lys330.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 25.5 kDa. Due to glycosylation, the protein migrates to 31-33 kDa based on Bis-Tris PAGE result.

Target Name:IgG1 FcSynonymsIgG1; Igh-4; RGD1359539; VH7183

Target Information:IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues.IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)