Description:NebuSelect™ Recombinant Human IL-1 Rrp2/IL-1 R6, hFc-tag(Cat#NBL-242506) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Asp20-Arg335.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 62.6 kDa. Due to glycosylation, the protein migrates to 75-110 kDa based on Bis-Tris PAGE result.

Target Name:IL-1 Rrp2/IL-1 R6SynonymsIL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R

Target Information:The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)