Description:NebuSelect™ Recombinant Human IL-18BP, hFc-tag(Cat#NBL-242459) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Thr31-Gly194.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 44.4 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.

Target Name:IL-18BPSynonymsIL-18BP; Igifbp

Target Information:Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)