Description:NebuSelect™ Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer, Avi-His-tag(Cat#NBL-242419) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 114 kDa (ITGAV)&79.1 kDa (ITGB6). Due to glycosylation, the protein migrates to 90-150 kDa based on Bis-Tris PAGE result.

Target Name:Integrin alpha V beta 6 (ITGAV&ITGB6) HeterodimerSynonymsIntegrin alpha V beta 6; ITGAV&ITGB6

Target Information:ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)