Description:NebuSelect™ Recombinant Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer, Avi-His-tag(Cat#NBL-242417) is expressed in HEK293 with His tag and Avi tag at the C-Terminus; It contains Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 114 kDa (ITGAV) and 76 kDa (ITGB8). Due to glycosylation, the protein migrates to 90-150 kDa based on Bis-Tris PAGE result.

Target Name:Integrin alpha V beta 8 (ITGAV&ITGB8) HeterodimerSynonymsIntegrin alpha V beta 8; TGAV&ITGB8

Target Information:Integrin αVβ8 is a heterodimeric cell surface receptor involved in various cellular processes, including cell adhesion, migration, and signaling. It is recognized for its unique role in activating TGF-β and has been implicated in immune responses and tissue homeostasis. Due to its distinctive structure and function, integrin αVβ8 is considered atypical among integrin family members.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)