Description:NebuSelect™ Recombinant Human LILRB4/CD85k/ILT3, hFc-tag(Cat#NBL-242358) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Gln22-Arg256.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 52.6 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result.

Target Name:LILRB4/CD85k/ILT3SynonymsHM18; ILT3; ILT-3; LILRB4; LIR5; CD85K

Target Information:LILRB4,also known as CD85k and LIR-5, ILT3,- is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)