Description:NebuSelect™ Recombinant Human PGF, hFc-tag(Cat#NBL-242198) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Leu19-Arg221.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 48.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Target Name:PGFSynonymsPlGF; PGF; PGFL; SHGC-10760; D12S1900; PlGF-2

Target Information:Placental growth factor (PGF) is another member of the VEGF family of cytokines with pro-angiogenic and pro-inflammatory effects. Retinal inhibition of PGF in combination with VEGF-A prevents vascular leakage and CNV possibly via modulating their own expression in mononuclear phagocytes. PGF-related, optimized strategies to target inflammation-mediated angiogenesis may help to increase efficacy and reduce non-responders in the treatment of wet AMD patients.

Amino Acid Sequence: Leu19-Arg221

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)