Description:NebuSelect™ Recombinant Human SFRP2, His-tag(Cat#NBL-242071) is expressed in HEK293 with His tag at the C-Terminus.It contains Leu25-Cys295.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 32.4 kDa. Due to glycosylation, the protein migrates to 34-38 kDa based on Bis-Tris PAGE result.

Target Name:SFRP2SynonymssFRP-2; SARP-1; Sarp1; Sdf5; Sfrp2; AI851596

Target Information:As biomarkers, DNA methylation is used to detect colorectal cancer (CRC) and make assessment of CRC prognosis. The published findings showed the association between the methylation of SFRP1, SFRP2, and WIF1, located in the Wnt signaling pathway, and the prognosis of CRC were not consistent. SFRP1, SFRP2, and WIF1 were frequently hypermethylated in CRC tumor tissues. It was apparent that the promoter hypermethylation of SFRP2 and co-hypermethylation of SFRP1 and SFRP2 might be considered as independent prognostic predictors for survival advantage of postoperative CRC patients.

Amino Acid Sequence: Leu25-Cys295

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)