Description:NebuSelect™ Recombinant Human SIRP Beta 1 isoform 3, Avi-His-tag(Cat#NBL-242065) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu30-Leu371.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 39.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Target Name:SIRP Beta 1 isoform 3SynonymsSIRP-beta-1 isoform 3; SIRPB1; CD172b; DKFZp686A05192; FLJ26614; 9930027N05Rik; SIRP-beta; Sirpb; Sirpb1; Sirpb1a

Target Information:Signal regulatory protein β1 (SIRPB1) is a signal regulatory protein member of the immunoglobulin superfamily and is capable of modulating receptor tyrosine kinase-coupled signaling. Copy number variations at the SIRPB1 locus were previously reported to associate with prostate cancer aggressiveness in patients.SIRPB1 gene amplification and overexpression were detected in prostate cancer specimens. The knockdown of SIRPB1 significantly suppressed cell growth in colony formation assays and cell mobility.

Amino Acid Sequence: Glu30-Leu371

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)