Description:NebuSelect™ Recombinant Human TFPI-2, His-tag(Cat#NBL-242041) is expressed in HEK293 with His tag at the C-Terminus.It contains Asp23-Lys213.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 22.9 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.

Target Name:TFPI-2SynonymsTFPI-2; PP5; TFPI2; REF1; TFPI-2REF1

Target Information:Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Moreover, in sputum from cystic fibrosis patients TFPI-2 C-terminal fragments are generated and found associated with immunoglobulins. Together our data describe a previously unknown host defense mechanism and therapeutic importance of TFPI-2 against invading Gram-negative bacterial pathogens.

Amino Acid Sequence: Asp23-Lys213.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)