Description:NebuSelect™ Recombinant Mouse TNFRSF12A/TWEAKR, hFc-tag(Cat#NBL-241997) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Glu28-Per80.

Species:Mouse

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 32.8 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Target Name:TNFRSF12A/TWEAKRSynonymsFGF-inducible 14; Fgfrp2; TNFRSF12A; FN14; CD266; TWEAKR

Target Information:Thyroid cancer (TC) is the most well-known endocrine neoplasia as well as a common malignant tumor in the head and neck.TNFRSF12A expression may be a potential useful prognostic molecular biomarker of bad survival in thyroid cancer, in addition, PPAR signaling pathway, insulin signaling pathway, mTOR signaling pathway may be the key pathway controlled by TNFRSF12A in thyroid cancer. Further experimental ought to be performed to demonstrate the biologic effect of TNFRSF12A.

Amino Acid Sequence: Glu28-Per80

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)