Description:NebuSelect™ Recombinant Human TRAIL R1/DR4/TNFRSF10A, hFc-tag(Cat#NBL-241992) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Pro34-Asn239.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 48.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:TRAIL R1/DR4/TNFRSF10ASynonymsDR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365

Target Information:Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.

Amino Acid Sequence: Pro34-Asn239

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)