Description:NebuSelect™ Recombinant Biotinylated Mouse PVRIG, Avi-hFc-tag(Cat#NBL-241909) is expressed in HEK293 with hFc tag and Avi tag at the C-Terminus.It contains Ser35-Asp165.

Species:Mouse

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 42.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.

Target Name:PVRIG

Target Information:Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.

Amino Acid Sequence: Ser35-Asp165

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)