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收藏Description:NebuSelect™ Recombinant Mouse LRRC15/LIB, His-tag(Cat#NBL-241876) is expressed in HEK293 with His tag at the C-Terminus.; It contains Tyr22-Gly536.
Species:Mouse
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 58.56 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Target Name:LRRC15/LIB
Target Information:The chimeric protein binds in vitro and in vivo to a specific element upstream of LRRC15, leading to dramatic transcriptional activation.- LRRC15 encodes a leucine-rich transmembrane protein, present at the leading edge of migrating cells, the expression of which in normal tissues is restricted to the invasive cytotrophoblast layer of the placenta; small interfering (siRNA)-mediated suppression of LRRC15 expression in breast cancer cells leads to abrogation of invasiveness in vitro.
Amino Acid Sequence: Tyr22-Gly536
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)