Description:NebuSelect™ Recombinant Mouse B7-H3/CD276, His-tag(Cat#NBL-241656) is expressed in HEK293 with His tag at the C-Terminus.It contains Val29-Ala248.

Species:Mouse

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 24.98 kDa. Due to glycosylation, the protein migrates to 42-52 kDa based on Bis-Tris PAGE result.

Target Name:B7-H3/CD276

Target Information:B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Amino Acid Sequence: Val29-Ala248

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)