Description:NebuSelect™ Recombinant Cynomolgus CD46, His-tag(Cat#NBL-241626) is expressed in HEK293 with His tag at the C-Terminus.It contains Cys35-Asp329.

Species:Cynomolgus

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 34.05 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Target Name:CD46

Target Information:CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)