Description:NebuSelect™ Recombinant Human OSMR&GP130, His-Flag-tag(Cat#NBL-241569) is expressed in HEK293 with His tag and Flag tag at the C-Terminus.It contains Glu28-Met740(OSMR)&Glu23-Glu619(GP130).

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 82.2 kDa(OSMR) and 68.83 kDa(GP130). Due to glycosylation, the protein migrates to 100-140 kDa based on Bis-Tris PAGE result.

Target Name:OSMR&GP130

Target Information:OSMR&gp130 is a type II receptor for OSM in humans. OSM can alternatively bind to a heterodimer of gp130 and LIF-R or of gp130 and OSMR (OSM receptor). On the basis of in vitro studies, the OSM ligand recruits a broader array of cell signaling pathways than most gp130 cytokines. OSMR and gp130 chains are widely expressed in connective tissue cells and tumor cells.

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)