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收藏Description:NebuSelect™ Recombinant Cynomolgus CD3E&CD3G/CD3 epsilon&CD3 gamma, His-Flag-tag(Cat#NBL-241407) is expressed in HEK293 with His tag and Flag tag at the C-Terminus.It contains Gln22-Asp117(CD3E) & Gln23-Thr113(CD3G).
Species:Cynomolgus
Expression System:HEK293
Molecular Weight: The protein has a predicted MW of 11.93 kDa (CD3E) and 11.52 kDa (CD3G). Due to glycosylation, the protein migrates to 13-23 kDa based on Bis-Tris PAGE result.
Target Name:CD3E&CD3G/CD3 epsilon&CD3 gamma
Target Information:T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
Purity:>95%
Endotoxin:<1EU/ug(LAL Method)