Description:NebuSelect™ Recombinant Human CDH17/Cadherin 17 Domain 7, hFc-tag(Cat#NBL-241370) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Ala668-Gly777.

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 38.42 kDa. Due to glycosylation, the protein migrates to 48-52 kDa based on Bis-Tris PAGE result.

Target Name:CDH17/Cadherin 17 Domain 7

Target Information:Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Amino Acid Sequence: Ala668-Gly777

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)