Description:NebuSelect™ Recombinant Human tPA, His-tag(Cat#NBL-241345) is expressed in HEK293 with His tag at the C-terminus.It contains Ser36-Pro562, which consists of two chains: chain A (Ser36-Arg310) and chain B (Ile311-Pro562).

Species:Human

Expression System:HEK293

Molecular Weight: The protein has a predicted MW of 60.13 kDa. The protein is activated by thermolysin and cleaved to a 2-chain protease, it migrates to 40-45 kDa (Chain A) and 35-40 kDa (Chain B) based on Bis-Tris PAGE result.

Target Name:tPA

Target Information:Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that thepredominant route for enhancing cell survival is via an mTORdependent mechanism.

Amino Acid Sequence: Ser36-Pro562

Purity:＞95%

Endotoxin:＜1EU/ug(LAL Method)